Rev.Adv.Mater.Sci. (RAMS)
No 1, Vol. 42, 2015, pages 1-5

NOVEL STRATEGIES FOR NEUROTRANSMITTER DETECTION AND MEASUREMENT USING ADVANCED MATERIALS

Igor Pantic, Jovana Paunovic, Ivan Dimitrijevic, Agata Błachnio, Aneta Przepiorka and Senka Pantic

Abstract

Several laboratories have recently published the findings indicating that nanomaterial-based biosensors could be very effective in detection of neurotransmitters in biological samples. Most of the research has been focused on monoamine neurotransmitters such as dopamine, serotonin and norepinephrine. These novel approaches have mostly been tested in in vitro conditions, however, there are indications that they might be also safely and effectively used in living organisms. In this concise review, we focus on the recent publications regarding the detection and measurement of monoamine neurotransmitters using nano-based sensors. We cover the research done during the past 5 years in the fields nanotechnology and nanomedicine. Finally, we discuss potential future approaches and trends in these research areas, as well as issues and challenges that scientists are faced with, when performing experimental or clinical work with nanomaterials.

full paper (pdf, 96 Kb)