Rev.Adv.Mater.Sci. (RAMS)
No 2, Vol. 34, 2013, pages 123-140


Mohammed Abedalwafa, Fujun Wang, Lu Wang and Chaojing Li


Biodegradable polymers have been used in biomedical applications generally, and in tissue engineering especially, due to good physical and biological properties. Poly-epsiloncaprolactone (PCL) is a one of biodegradable polymers, which has a long time of degradation. But the mechanical properties, biodegradability and biocompatibility of the pure PCL cannot meet up with the requirement for some of the biomedical applications such as bone tissue engineering, for that many researches have established to focus on the modification of the PCL. In this review, different results on the fabrication of PCL for specific field of tissue engineering, tissue engineering incorporated in different PCL, surface modifications, blending with other polymers and their micro-porous structure are represented in brief outcomes. In addition dissolution of PCL in different organic solvents and the effect on their properties was attainable. Moreover, the physical and biological properties of PCL for different type of tissue engineering applications (hard and soft tissue) are obtainable.

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