No 3, Vol. 5, 2003 
 

FABRICATION OF DNA MONOLAYERS ON GOLD SUBSTRATES AND GUIDING OF DNA WITH ELECTRIC FIELD

S. Tuukkanen1, J. Virtanen2, V. P. Hytönen3, M.S. Kulomaa3 and P. Törmä1

1 Department of Physics, University of Jyväskylä, P.O.Box 35,
FIN-40014 University of Jyväskylä, Finland
2 Department of Chemistry, University of Jyväskylä, P.O.Box 35,
FIN-40014 University of Jyväskylä, Finland
3 Department of Biological and Environmental Science, University of Jyväskylä,
P.O.Box 35, FIN-40014 University of Jyväskylä, Finland

Abstract

We report electrically controlled selective coating of gold electrodes with mixed monolayers of oligonucleotides and alkanethiol passivation molecules. Gold nanoparticles are used as labels for visualization and voltage between the electrodes is applied for guiding the oligonucleotides. We discuss the efficiency of the guiding and monolayer preparation procedure.

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